Gen Fujii Selected Research

Intestinal Polyps

4/2020	Theracurmin inhibits intestinal polyp development in Apc-mutant mice by inhibiting inflammation-related factors.
1/2020	The Radical Scavenger NZ-419 Suppresses Intestinal Polyp Development in Apc-Mutant Mice.
1/2019	Novel screening system revealed that intracellular cholesterol trafficking can be a good target for colon cancer prevention.
5/2017	Chemopreventive effects of a low-side-effect antibiotic drug, erythromycin, on mouse intestinal tumors.
4/2017	Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice.
4/2017	Preventive Effects of Heat-Killed Enterococcus faecalis Strain EC-12 on Mouse Intestinal Tumor Development.
2/2016	Irsogladine maleate, a gastric mucosal protectant, suppresses intestinal polyp development in Apc-mutant mice.
11/2015	Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice.
7/2015	Suppression of intestinal carcinogenesis in Apc-mutant mice by limonin.
3/2015	Involvement of NADPH oxidases in suppression of cyclooxygenase-2 promoter-dependent transcriptional activities by sesamol.

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Gen Fujii Research Topics

Disease

15	Carcinogenesis 11/2021 - 01/2012
13	Intestinal Polyps 04/2020 - 01/2013
12	Colorectal Neoplasms (Colorectal Cancer) 03/2022 - 10/2005
11	Neoplasms (Cancer) 04/2020 - 10/2005
10	Colonic Neoplasms (Colon Cancer) 11/2019 - 01/2012
9	Polyps 04/2020 - 01/2013
3	Obesity 07/2021 - 01/2012
3	Inflammation (Inflammations) 04/2020 - 01/2012
3	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2019 - 01/2016
3	Aberrant Crypt Foci 08/2017 - 01/2012
3	Hepatocellular Carcinoma (Hepatoma) 02/2014 - 03/2003
1	Body Weight (Weight, Body) 07/2021
1	Chronic Renal Insufficiency 01/2020
1	Hypertriglyceridemia 01/2016
1	Overweight 01/2016
1	Pancreatitis 03/2013
1	Pancreatic Neoplasms (Pancreatic Cancer) 03/2013
1	Hyperlipidemias (Hyperlipidemia) 03/2013

Drug/Important Bio-Agent (IBA)

12	Messenger RNA (mRNA)IBA 04/2020 - 10/2005
5	Interleukin-6 (Interleukin 6)IBA 04/2020 - 01/2012
4	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 05/2017 - 03/2013
3	Pharmaceutical PreparationsIBA 11/2021 - 05/2017
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 11/2015
3	AzoxymethaneIBA 08/2017 - 01/2012
3	CateninsIBA 04/2017 - 01/2015
3	Biological ProductsIBA 07/2015 - 01/2012
2	Insulin (Novolin)FDA Link 07/2021 - 01/2012
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2020 - 07/2015
2	AntioxidantsIBA 01/2020 - 11/2019
2	Transcription Factors (Transcription Factor)IBA 11/2019 - 08/2017
2	EnzymesIBA 11/2019 - 11/2015
2	LuciferasesIBA 11/2019 - 08/2017
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 08/2017 - 05/2017
2	TCF Transcription FactorsIBA 04/2017 - 07/2015
2	NADPH Oxidases (NAD(P)H oxidase)IBA 11/2015 - 03/2015
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 11/2015 - 03/2013
2	sesamolIBA 03/2015 - 03/2014
2	AdipokinesIBA 03/2013 - 01/2012
2	beta CateninIBA 10/2005 - 03/2003
2	Proteins (Proteins, Gene)FDA Link 10/2005 - 10/2004
1	colibactinIBA 03/2022
1	ArtesunateIBA 11/2021
1	Antimalarials (Antimalarial Agents)IBA 11/2021
1	Dietary CalciumIBA 07/2021
1	CalciumIBA 07/2021
1	Dietary Fiber FDA Link 05/2020
1	PowdersIBA 05/2020
1	InterleukinsIBA 04/2020
1	CurcuminIBA 04/2020
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 04/2020
1	CreatinineIBA 01/2020
1	5-hydroxy-1-methylhydantoinIBA 01/2020
1	Hydroxyl RadicalIBA 01/2020
1	Nuclear Antigens (Extractable Nuclear Antigens)IBA 01/2020
1	CholesterolIBA 01/2019
1	NF-kappa B (NF-kB)IBA 01/2019
1	Itraconazole (Sporanox)FDA LinkGeneric 01/2019
1	fucoxanthinolIBA 01/2019
1	Propidium (Propidium Iodide)IBA 01/2019
1	Annexin A5IBA 01/2019
1	Anticarcinogenic AgentsIBA 08/2017
1	Anti-Bacterial Agents (Antibiotics)IBA 05/2017
1	Erythromycin (Erycette)FDA LinkGeneric 05/2017
1	Carbon DioxideIBA 04/2017
1	CytokinesIBA 04/2017
1	Acetazolamide (Diamox)FDA LinkGeneric 04/2017
1	Protons (Proton)IBA 04/2017
1	Bicarbonates (Hydrogen Carbonate)IBA 04/2017
1	Carbonic Anhydrase InhibitorsIBA 04/2017
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 04/2017
1	Cyclin D1IBA 04/2017
1	irsogladineIBA 02/2016
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2016
1	acetovanillone (apocynin)IBA 11/2015
1	Trefoil FactorsIBA 08/2015
1	LimoninsIBA 07/2015
1	limoninIBA 07/2015
1	LignansIBA 03/2015
1	NADPH Oxidase 1IBA 03/2015
1	NADP (NADPH)IBA 03/2015
1	Interleukin-17 (Interleukin 17)IBA 01/2015
1	GalactosidasesIBA 03/2014
1	ProstaglandinsIBA 03/2014
1	Prostaglandin-E SynthasesIBA 03/2014
1	Trans-Activators (Trans-Acting Factor)IBA 02/2014
1	Mitogen-Activated Protein KinasesIBA 02/2014
1	Plasminogen Activator Inhibitor 1IBA 01/2014
1	Synthetic DrugsIBA 07/2013
1	nitrosobis(2-oxopropyl)amine (NBOP)IBA 03/2013
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 03/2013
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2013
1	Verapamil (Calan)FDA LinkGeneric 01/2013
1	LigandsIBA 01/2012
1	SK-1009IBA 01/2012
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2012
1	Pioglitazone (Actos)FDA Link 01/2012
1	PPAR gammaIBA 01/2012

Therapy/Procedure

2	Chemoprevention 01/2016 - 07/2013
1	Colectomy 01/2016
1	Therapeutics 02/2014